Cytokine release syndrome

Thought I'd give you all a little bit of information regarding the main side effects of Lemtrada infusion, they package this up and call it a "Cytokine release syndrome". This is:

Cytokine-release syndrome is a symptom complex associated with the use of many monoclonal antibodies. Commonly referred to as an infusion reaction, it results from the release of cytokines from cells targeted by the antibody as well as immune effector cells recruited to the area. When cytokines are released into the circulation, systemic symptoms such as fever, nausea, chills, hypotension, tachycardia, asthenia, headache, rash, scratchy throat, and dyspnea can result. In most patients, the symptoms are mild to moderate in severity and are managed easily. - http://www.ncbi.nlm.nih.gov/pubmed/17471824

Lemtrada is a monoclonal antibody and the cytokine-release syndrome presents itself as follows, the ones I have experienced are in bold:

LEMTRADA causes cytokine release syndrome resulting in infusion reactions. Serious reactions occurred in 3% of these patients and included anaphylaxis in 2 patients (including anaphylactic shock), angioedema, bronchospasm, hypotension, chest pain, bradycardia, tachycardia (including atrial fibrillation), transient neurologic symptoms, hypertension, headache, pyrexia, and rash. - http://www.lemtradarems.com/Docs/Pdf/LEMTRADA-HCP-ISI.pdf

All of these were easily managed and as long as I kept up my antihistamines, pain killers, ventolin and antivirals I knew I was good.